ABORTIFACIENTS are drugs used to induce abortion or miscarriage. A number of types of drug have been used, but commonly the progestogen antagonist mifepristone is used (orally) and/or the prostaglandin gemeprost or dinoprostone (by the extra-amniotic route) (see PROSTANOID RECEPTOR AGONISTS). A wide variety of the synthetic or natural agents, e.g. quinine, urea, ergot alkaloids, including ergotmetrine, and certain microbial toxins, may cause abortion (depending on dose and route of administration).
See also LUTEOLYTIC AGENTS.