ANTIAGEING AGENTS have yet to be discovered. However, many factors involved in physical deterioration have been identified, and some palliative measures to slow these processes, particularly in relation to cardiovascular disease, are well known, such as dietary restriction, exercise etc. There have been many investigations of the effects of placental extracts and other hormonal treatments but the results are unconvincing. More recently, there have been hopeful results from studies of antioxidants, superoxide dismutase modifiers and free-radical scavengers. Increasingly, gene-expression factors are recognized to form a vital role in the rate of ageing. Treatments in relation to age-related neurodegenerative diseases (e.g. Alzheimer’s disease and Parkinson’s disease) are of obvious importance, though more in relation to quality of life.