Medical Uses Cranberries are used to prevent urinary tract infections and to treat mild urinary tract infections. Historical Uses Native Americans and Europeans who settled in the United States used cranberries for food and medicinal purposes. Around 1923, scientists discovered that people who consumed cranberries had more acidic urine than those who did not. Growth The cranberry is related to the blueberry and bilberry. Cranberries prefer bogs, cool weather, and acidic soils. Cranberry: Part Used • Fruit (red berries) Major Chemical Compounds • Proanthocyanidins • Flavonoids • Fructose • Vitamin C Cranberry: Clinical Uses Cranberries are used to prevent urinary tract infections (UTIs) and are useful in treating mild UTIs. Mechanism of Action Cranberry prevents the adherence of bacteria to the walls of the urinary tract because the fructose compound inhibits adhesion of Escherichia coli () and proanthocyanidins inhibit adhesion of E. coli to uroepithelial cells. Cranberry: Dosage Capsules: 300 to 400 mg twice a day of standardized, concentrated cranberry extract capsules. Berries or juice: The daily amount needed is IV2 ounces of fresh or frozen cranberries or 3 ounces of cranberry Read more […]
Archive for category Cranberry'
Vaccinium macrocarpon Aiton (Ericaceae) Synonym(s) and related species Large cranberry (Vaccinium macrocarpon) is the cultivated species. European cranberry or Mossberry (Vaccinium oxycoccus) has also been used. Pharmacopoeias Cranberry Liquid Preparation (The United States Ph 32). Constituents The berries contain anthocyanins and proanthocyanidins (mainly oligomers of epicatechin), and organic acids including malic, citric, quinic and benzoic acids. Note that, although salicylic acid does not appear as a constituent of the juice in many cranberry monographs, some studies have shown low levels of salicylates in commercial cranberry juice (e.g. 7mg/L), which resulted in detectable plasma and urine levels of salicylic acid in women who drank 250 mL of cranberry juice three times daily. Use and indications The main use of cranberries and cranberry juice is for the prevention and treatment of urinary tract infections, although they have also been used for blood and digestive disorders. Cranberries are commonly used in food and beverages. Pharmacokinetics There is high absorption and excretion of cranberry anthocyanins in human urine, as shown by a study where 11 healthy subjects drank 200 mL of cranberry Read more […]