Archive for category Ephedra'

Herb-Drug Interactions: Ephedra

Ephedra sinica Stapf., Ephedra gerardiana Wall., Ephedra equisetina Bunge (Ephedraceae) Synonym(s) and related species Ma huang. Constituents The main active components of ephedra are the amines (sometimes referred to as alkaloids, or more properly pseudoalkaloids) ephedrine, pseudoephedrine, norephedrine, norpseudoephedrine, ALmethylephedrine, ephedroxane, maokonine, a series of ephedradines and others. Other constituents include the diterpenes ephedrannin A and mahuannin, catechins, and a trace of volatile oil containing terpinen-4-ol, alpha-terpineol, linalool and other monoterpenes. Use and indications Ephedra is used traditionally for asthma, bronchitis, hayfever and colds, but recently the herb has become liable to abuse as a stimulant and slimming aid. For this reason the herb has been banned by the FDA in the US. Its main active constituents are ephedrine and pseudoephedrine; however, ephedra herb is claimed to have many more effects than those ascribed to ephedrine and its derivatives. It is these compounds that also give rise to the toxic effects of ephedra. Pharmacokinetics No relevant pharmacokinetic data found. Interactions overview Ephedra herb contains ephedrine and pseudoephedrine, and Read more […]