Archive for category Willow'

Herb-Drug Interactions: Willow

Salix species (Salicaceae) Synonym(s) and related species European willow, Salix, White willow. Salix alba L., Salix cinerea L., Salix daphnoides, Salix fragilis L., Salix pentandra L., Salix purpurea L. Pharmacopoeias Willow Bark (British Ph 2009, European Ph 2008); Willow Bark Dry Extract (British Ph 2009, European Ph, 6th ed., 2008 and Supplements 6.1, 6.2, 6.3 and 6.4). Constituents The bark of willow contains the phenolic glycosides salicin (up to 10%), acetylsalicin, salicortin, salireposide, picein, triandrin. Esters of salicylic acid and salicyl alcohol, and flavonoids and tannins are also present. Extracts are sometimes standardised to a minimum of 1.5% of total salicylic derivatives, expressed as salicin (British Ph 2009, European Ph, 6th ed., 2008 and Supplements 6.1, 6.2, 6.3 and 6.4). Use and indications The bark of willow is reported to have analgesic, anti-inflammatory, antipyretic and astringent properties. It has long been used for treating all kinds of fevers, headache, influenza, rheumatism, gout and arthritis. Pharmacokinetics In a pharmacokinetic study, 10 healthy subjects were given two oral doses of Salix purpurea bark extract, each standardised to contain 120 mg of salicin, 3 Read more […]