Dioscorea villosa L. (Dioscoreaceae)
The major constituents of the root and rhizome are saponins based mainly on diosgenin and other sapogenins; they include dioscin and dioscorin.
Use and indications
Traditionally, wild yam was used to treat rheumatism and intestinal colic. However, more recently wild yam extract has found favour as a form of topical hormone replacement therapy for women. It is often claimed that wild yam is a source of ‘natural progesterone’, but this is not the case – it is a source of diosgenin, which is used by the pharmaceutical industry as a chemical precursor for the production of progesterone.
No relevant pharmacokinetic data found.
No interactions with wild yam found.