Although salicylates are present, they appear to cause less gastrointestinal irritation than acetylsalicylic acid. In fact, a meadowsweet preparation protected against acetylsalicylic acid-induced stomach ulcers in vivo.
Controlled studies are not available, therefore interactions are based on evidence of activity and are largely theoretical and speculative.
As increased bleeding may occur, observe patients taking warfarin concurrently. The herb has been shown to exert anticoagulant activity in vitro and in vivo, but the clinical significance of these results is unknown.
ASPIRIN AND SIMPLE ANALGESICS
Contraindications and Precautions
Meadowsweet should not betaken by people with salicylate sensitivity. Suspend use of concentrated extracts 1 week before major surgery.