Meadowsweet: Interactions. Contraindications. Pregnancy Use

Adverse Reactions

Although salicylates are present, they appear to cause less gastrointestinal irritation than acetylsalicylic acid. In fact, a meadowsweet preparation protected against acetylsalicylic acid-induced stomach ulcers in vivo.

Significant Interactions

Controlled studies are not available, therefore interactions are based on evidence of activity and are largely theoretical and speculative.

WARFARIN

As increased bleeding may occur, observe patients taking warfarin concurrently. The herb has been shown to exert anticoagulant activity in vitro and in vivo, but the clinical significance of these results is unknown.

ASPIRIN AND SIMPLE ANALGESICS

Theoretically, meadowsweet may enhance anti-inflammatory and antiplatelet effects Observe patients taking this combination — beneficial interaction possible.

Contraindications and Precautions

Meadowsweet should not betaken by people with salicylate sensitivity. Suspend use of concentrated extracts 1 week before major surgery.

Pregnancy Use

Not recommended.