Saw palmetto: Practice Points – Patient Counselling. FAQ

• Substantial scientific evidence has shown that saw palmetto is an effective treatment for stages 1 and 2 of BPH in cases where the diagnosis of cancer is negative. It is as effective as finasteride and alpha-adrenoreceptor antagonist drugs such as tamsulosin and alfuzosin, although prazosin may be slightly more effective. • Typically, symptom reduction is experienced within 1-2 months’ treatment, which is well tolerated, and associated with fewer side effects than finasteride and tamsulosin. • The herb does not affect PSA levels therefore PSA test results will be unaffected. • If symptoms worsen, blood is detected in the urine or acute urinary retention occurs, seek professional advice. Answers to Patients’ Frequently Asked Questions What will this herb do for me? Saw palmetto has been investigated in numerous scientific studies and shown to reduce symptoms of enlarged prostate with few side-effects. There is also some early research suggesting it may be useful in some forms of hair loss and prostatitis. When will it start to work? Symptom relief for enlarged prostate is generally experienced within 4-8 weeks. Are there any safety issues? Saw palmetto is well tolerated; however, Read more […]

Saw palmetto: Clinical Use. Dosage

The most studied saw palmetto preparation is a commercial product known as Permixon (Pierre Fabre Medicament, Castres, France), which is a liposterolic extract consisting of 80% free (e.g. 94 g/100 g extract) and 7% esterified fatty acids, as well as small amounts of sterols (beta-sitosterol, campesterol, stigmasterol, cycloartenol), and a minimum percentage of polyprenic compounds, arabinose, glucose, galactose, uronic acid, and flavonoids. BENIGN PROSTATIC HYPERTROPHY Saw palmetto extracts are extremely popular in Europe where herbal preparations represent approximately one-third of total sales of all therapeutic agents sold for the treatment of BPH. Substantial evidence suggests that saw palmetto is an effective treatment for stages 1 and 2 of BPH. A 2002 Cochrane review assessing the results from 21 randomised trials involving 3139 men concluded that saw palmetto improves urinary scores, symptoms and urinary flow measures compared with placebo, with effects on symptoms scores and peak urine flow similar to the pharmaceutical drug finasteride. Additionally, its use is associated with fewer adverse effects compared with finasteride and typically, symptomatic relief is reported more quickly. In 2004, an updated Read more […]