Pygeum: Interactions. Pregnancy Use. Practice Points. FAQ

Adverse Reactions

Pygeum is well tolerated with side-effects similar to placebo. Mild gastrointestinal discomfort has been reported.

Significant Interactions

None known.

Contraindications and Precautions

People with known allergies should avoid use.

Pregnancy Use

Safety not scientifically established; however, it is not used for any indication that would cause a pregnant woman to use it.

Practice Points / Patient Counselling

• Pygeum is a popular treatment in Europe for benign prostatic hypertrophy.

• A systematic review of 18 clinical studies found it has significant effects in BPH such as increasing peak urine, reducing residual urine volume and producing an overall improvement in symptoms.

• Several different mechanisms of action have been identified using animal models which would explain its effectiveness in BPH.

• According to clinical studies the dose used is 50-100 mg twice daily of standardised extract for BPH and the treatment is well tolerated.

• Over-harvesting has meant the tree is now considered endangered and efforts are being made to protect it from extinction.

Answers to Patients’ Frequently Asked Questions

What will this herb do for me?

Standardised pygeum extract is an effective treatment in benign prostate enlargement or inflammation and improves several symptoms.

When will it start to work?

Some men will notice an improvement in symptoms after 4 weeks; however, others will require longer term treatment.

Are there any safety issues?

It is a well tolerated treatment but should not be used by people with a known allergy to the plant. If symptoms worsen, seek professional advice.